Reading the show notes in the original entry has reminded me that this game used the C key for crouch and Ctrl for sprint, which is just silly bananas. However, maybe they’re just trying to capture the true spirit of System Shock, which has always used goofy and unconventional controls.
In the original System Shock (drink!) there was no concept of mouselook. All looking, turning, and movement was done with the keyboard. The advantage of this system was that you could shoot at things that were anywhere in view just by clicking on them. The downside of this system was that it was completely horrible.
System Shock 2 had basically normal controls by modern standards, except the default key mappings were really goofy. The A and D keys were used for turning. If you wanted to step to the side, you used Z and C. Mouselook was a few years old by this point, so this was a break from convention. I do wonder how many people used the controls with these defaults? I hope not many, since the resulting muscle-memory would ruin you for all other first-person PC games until you could learn to walk all over again.